Cyclizine

Do not take Cyclizine Hydrochloride Tablets:

• if you are allergic to cyclizine hydrochloride or any of the other ingredients of this medicine (allergic reactions include mild symptoms such as itching and/or rash. More severe symptoms include swelling of the face, lips, tongue and / or throat with difficulty in swallowing or breathing)
• if you have been drinking alcohol. The anti-vomiting properties of cyclizine may increase the toxicity of alcohol.

Warnings and precautions

Talk to your doctor, pharmacist or nurse before taking Cyclizine Hydrochloride Tablets if you:

• suffer from an eye disease caused by a rise of pressure within the eye (glaucoma)
• suffer from urinary retention (experience difficulty passing urine)
• have an obstructive bowel condition
• have any liver problems
• suffer from phaeochromocytoma (tumour of the medulla of the adrenal glands)
• suffer from high blood pressure
• have epilepsy
• are a man and you suffer from an enlarged prostate gland (difficulty or slowness passing urine)
• have been told your heart is not working properly (heart failure)
• suffer from an inherited disorder which can lead to a sensitivity to sunlight (porphyria)

Other medicines and Cyclizine Hydrochloride Tablets

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines especially the following:

• medicines for problems such as depression, anxiety or difficulty in sleeping
• strong painkillers such as pethidine
• any medicine which belong to a group of medicines called anticholinergics.

Cyclizine Hydrochloride Tablets with food and drink

Alcohol should be avoided when you are taking Cyclizine Hydrochloride Tablets.

Pregnancy and breast-feeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Driving and using machines

You can drive while taking Cyclizine Hydrochloride Tablets but do not drive until you know how the tablets affect you. Cyclizine Hydrochloride Tablets may make you feel dizzy. If they affect you in this way, do not drive or operate any machinery.

Cyclizine Hydrochloride Tablets contain lactose.

If you have been told that you have intolerance to some sugars, talk to your doctor before taking these tablets.

Always take this medicine exactly as your doctor or pharmacist has told you.

Check with your doctor, pharmacist or nurse if you are not sure.

Adults

The recommended dose is one tablet up to three times daily.

Each tablet contains 50 mg of the active ingredient, cyclizine hydrochloride.

The other ingredients include: lactose, potato starch, acacia and magnesium stearate.

This medicine can cause side effects like all medicines, although not everybody gets them.

If you notice:

• itching or skin rashes
• swelling of the face, lips or throat
• difficulty in breathing or wheeziness

Stop taking this medicine and tell your doctor immediately. These may be signs of an allergic reaction.

The following side effects are reported with a not known frequency (frequency cannot be estimated from the available data):

• skin rashes or itching
• drowsiness
• lack of coordination
• headache
• a dry mouth, nose or throat
• blurred vision
• involuntary rolling of the eyes
• fast heartbeat
• irregular heartbeat
• difficulty in passing water
• constipation
• heartburn (reflux)
• feeling sick
• being sick
• diarrhoea
• stomach pain
• loss of appetite
• restlessness
• nervousness
• euphoria
• difficulty in sleeping
• ringing in the ears
• seeing or hearing things that are not really there (hallucinations)
• decrease in muscle tone
• unusual body movements, particularly of your hands, arms or legs
• muscle twitches, spasms or tremors
• seizures
• being confused, disorientated or unaware
• dizziness
• feeling weak
• decreased consciousness
• temporary difficulty in speaking
• high blood pressure
• low blood pressure
• pins and needles
• yellowing of the skin and the whites of your eyes (jaundice)
• a red or brownish patch which appears at the same spot each time you take the medicine
• an increased sensitivity to sunlight (photosensitivity)
• inflammation of the liver (hepatitis) or problems with the liver
• reduced rate of breathing (apnoea)
• reduction in the production of a type of white blood cell making infection more likely (agranulocytosis).
• unpleasant sensation or an overwhelming urge to move the legs (also called Restless Legs Syndrome).
• If you feel very tired, experience unexpected bruising or bleeding or more infections (e.g. colds and sore throats) than usual please tell your doctor. Your doctor may decide to conduct tests on your blood periodically as a result of these symptoms.

If any of the side effects become severe or you notice any not listed side effects, please tell your doctor or pharmacist immediately.